No |
Date | Topics |
Chapter in Smith |
Lecture Materials | External Links |
| 1 | 8/28 | Modern Definition of "Organic". Wohler's experiment disproving vitalism. | na | 
(powerpoints from 2005 lecture) |
http://wohlersynthesis.quickseek.com/ |
| 2 | 8/30 | Lewis Structures and Formal Charge | 1.1-1.4 |
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| 3 | 9/1 | Resonance, VSEPR | 1.5-1.6 |
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| 4 | 9/6 | Valence Bond Theory and Hybrid Orbitals. | 1.5-1.6 | |
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| 5 | 9/8 | Hybridization and Bond Length/Strength. Molecular Polarity. | 1 | |
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| 6 | 9/11 | Naming Alkanes and Cycloalkanes. Alkyl Groups. | 4 |
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http://viscog.beckman.uiuc.edu/grafs/demos/15.html |
| 7 | 9/13 | Functional group families. Intermolecular forces and bp prediction. | 3 |
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| 8 | 9/15 | Predicting melting points and solubility. Alkane reactions. | 3 |
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| 9 | 9/18 | NMR Basics | 15 |
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http://vam.anest.ufl.edu/forensics/nmr.html |
| 10 | 9/20 | Acid/base reactions. Predicting acidity. | 2 |
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| 11 | 9/22 | Predicting acidity continued. Types of organic reactions. | 2, 6 |
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| 12 | 9/25 | Types of organic reactions. Predicting equilibrium constants and rates. | 6 |
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| 13 | 9/27 | Kinetics and Collision Theory | 6 |
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| 9/29 | Exam 1 | ||||
| 14 | 10/2 | Ring strain and cis/trans isomerism in cycloalkanes. Cyclohexane chair conformers. | 4 |
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http://www.owlnet.rice.edu/~chem251/documents/Vollhardt_4.ppt |
| 15 | 10/4 | Alkyl Halides. Nomenclature and Reactivity. Intro to Nucleophilic Substitution. | 7 |
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| 16 | 10/6 | Naming Enantiomers - R/S Designations | 5 |
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| 17 | 10/9 | Other types of chiral compounds. Mechanisms of nucleophilic substitution. Facts about the SN2 reaction. | 7 |
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http://www.sussex.ac.uk/Users/kafj6/stereo/lecture1.pdf |
| 18 | 10/11 | Stereogenic nitrogen? Transition state explanation of steric hindrance. Facts about the SN1 reaction - carbocation stability. | 7 |
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| 19 | 10/16 | Nucleophiles and Leaving Groups. | 7 |
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| 20 | 10/18 | Solvent effects in SN reactions. | 7 |
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| 21 | 10/20 | Proton NMR - Number or signals and chemical shift. | 15 |
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| 22 | 10/23 | Proton NMR - Chemical shifts, peak integrals and proton counts, spin-spin splitting. | 15 |
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| 23 | 10/25 | Cyclohexane conformations revisited. Intro to Chapter 8 | 4, 8 |
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| 24 | 10/30 | E2 Elimination of alkyl halides. Zaitsev's rule. | 8 |
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| 25 | 11/1 | E2 elimination, Rate effects and stereochemistry. | 8 |  |
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| 26 | 11/3 | Mass spectrometry. | 14 | |
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| 27 | 11/6 | Mechanisms of elimination. E1, E2, E1cB. | 8 | |
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| 28 | 11/8 | Predicting the reaction and mechanism. Bases used for E2. SN2, E2, or SN1/E1. | 8 | |
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| 29 | 11/13 | Preparation of alkynes by E2. Naming of alcohols and ethers. Physical properties and important simple alcohols and ethers. | 8, 9 | |
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| 30 | 11/15 | Naming of cyclic ethers including epoxides. Crown ethers and phase transfer catalysis. | 9 | |
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| 31 | 11/17 | Alcohols: reaction with HX. Carbocation rearrangements. | 9 | |
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| 32 | 11/27 | IR Spectroscopy. | 14 |
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| 33 | 11/29 | Alcohol reactions. Alternative reagents for halogenation and dehydration. | 9 |
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| 34 | 12/1 | Conversion of alcohols to tosylates. Stereochemistry. | 9 | |
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| 35 | 12/4 | Ether reactions. Cleavage by acid. Epoxide reactions. | 9 | |
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| 36 | 12/6 | Solving unknowns using NMR, MS, and IR spectra. | 14, 15 | |
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| 37 | 12/8 | Epoxide reactions in synthesis. Epoxides in biochemistry. | 9 | |