|
No
|
Date |
Topics
|
Chapter
|
PowerPoint
|
| 1 |
8/24 |
The
structural theory. Review of Lewis
Structures.
|
1.1-1.4
|
|
| 2 |
8/26 |
Lewis
Structures and Formal Charge. Resonance
structures.
|
1.1-1.6
|
|
| 3 |
8/28 |
VSEPR
Theory and Molecular Polarity.
|
1.7-1.10
|
|
| 4 |
8/31
|
Valence bond theory. Hybrid
orbitals. Pi and sigma bonds.
|
1.10-1.12
|
|
| 5 |
9/2 |
Naming alkanes and finding isomers.
Naming
of Branched Alkyl Groups.
|
4.1-4.5
|
|
| 6 |
9/4 |
Naming
of Branched Alkyl Groups. Cycloalkanes.
Finding isomers of cycloalkanes, alcohols
and amines. Functional group families.
|
4, 3.1
|
|
| 7 |
9/9 |
Intermolecular
forces and physical properties. Boiling
points, melting points. Solubility.
|
3
|
|
| 8 |
9/11 |
Acid/base
reactions. Predicting acidity.
|
2
|
|
| 9 |
9/14 |
More on predicting acidity and
predicting basicity. Applying acidity
predictions.
|
2
|
|
| 10 |
9/16 |
Common acids and
bases. Combustion and
cycloalkane stability.
|
|
|
| 11 |
9/18 |
C-13 NMR |
14 |
|
| 11 |
9/21 |
Conformations of
cycloalkanes.
Naming of
bicyclic alkanes. |
4
|
|
| 12 |
9/23 |
Conformations of
substituted cyclohexanes.
|
4 |
|
|
9/25 |
Exam 1 |
1-4, 14
(C-13 NMR)
|
|
| 13 |
9/28 |
Proton NMR |
14 |
|
| lab |
|
IR |
14 |
|
| 14 |
9/30
|
Proton NMR
|
14
|
|
| 15 |
10/2
|
Understanding
organic reactions. Predicting equilibrium
constants.
|
6
|
|
| 16 |
10/5 |
Kinetics
and Collision Theory. Transition State
Theory. The Hammond Postulate.
|
|
|
| 17 |
10/7 |
Mechanisms of
nucleophilic substitution. SN2 and
SN1 mechanisms. Kinetics. Steric
hindrance and carbocation stability. |
7
|
|
| 18 |
10/9 |
SN2
and SN1. Nucleophiles and Leaving
Groups.
|
7
|
|
| 19 |
10/12 |
Solvent
effects in SN reactions. Predicting SN2
or SN1 mechanism.
Stereochemistry of SN
reactions.
|
7
|
|
| 20 |
10/14 |
Carbocation
rearrangements. SN2 reactions in
synthesis.
|
9.9, 7
|
|
| 21 |
10/16 |
Properties
of Diastereomers and Enantiomers. Optical
activity. Racemic mixtures, chiral
non-racemic, and achiral compounds. |
5
|
|
| 22 |
10/19 |
Resolution
of racemic mixtures. Other types of chiral
compounds. |
5 |
|
| 23 |
10/21 |
Mass Spectrometry
|
13
|
|
24
|
10/23 |
Lab
Quizzes: MM3 and Expt 1
|
|
|
| |
10/26 |
|
5-7,
9.9, 13 (IR), 14 (proton NMR)
|
|
| 25 |
10/28 |
1,2-Elimination
of Alkyl Halides. The E1, E2, and E1cb
mechanisms. Details of the E2
transition state. Rate effects.
|
8
|
|
| 26 |
10/30 |
Zaitsev's
rule. Predicting when
the mechanism is E1 or E2. Rearrangements
in E1 reactions. Bulky bases
used for E2 reactions.
|
8
|
|
| 27 |
11/2 |
Stereochemistry
of E2 and E1 reactions. |
8
|
|
| 28 |
11/4 |
Predicting
the reaction and mechanism. SN2,
E2, or SN1/E1. Preparation of
alkynes by E2.
|
8
|
|
| 29 |
11/6 |
Alcohol
reactions. Conversion to alkyl halides using
HX, SOCl2, or PX3.
Conversion of alcohols to tosylates.
|
9
|
|
| 30 |
11/9 |
Alcohol reactions. Acid-catalyzed
dehydration. Carbocation rearrangements, Use
of POCl3 and
pyridine for dehydration.
|
9
|
|
| 31 |
11/13 |
Reaction of
alcohols with strong bases to form
alkoxides. Williamson ether synthesis.Naming
and Reactions of Ethers.
|
9.14-9.15
|
|
| 32 |
11/16 |
Epoxide
ring-opening reactions. Stereochemistry and
regiochemistry.
|
9
|
|
|
11/18 |
Exam 3 |
7-9, 13 (MS)
|
|
| 34 |
11/20 |
Addition
of HX and X2 to alkenes.
Stereochemistry of HX and X2
additions.
|
10
|
|
| 35 |
11/23 |
Alkenes
|
10
|
|
| 36 |
11/30 |
Alkenes
|
10
|
|
| 37 |
12/2 |
Alkynes
|
11
|
|
| 38 |
12/4 |
Alkynes
|
11
|
|
| 38 |
12/9 |
Exam
4
|
10-11
|
|