No |
Date | Topics |
Chapter in Smith |
Lecture Notes |
1 |
1/13 | Bp and mp of cis vs trans alkenes. Triacylglycerols or Fats. | 10.4, 10.6, 26.3 |  |
2 |
1/18 | Alkene preparation. Double bond addition reactions. | 10.7-10.11 |
 |
3 |
1/20 | Hydrohalogenation mechanism. Hydration. | 10.9-10.12 | |
4 |
1/23 | Hydration showing R+ rearrangement. Halogenation stereochemistry and mechanism. | 10.12-10.15 | |
5 |
1/25 | Halohydrin formation. Hydroboration. | 10 | |
6 |
1/27 | Hydroboration using 9-BBN. Synthesis. | 10 | |
7 |
1/30 | Alkyne acidity. Acetylide ions as nucleophiles. HX addition. | 11 | |
8 |
2/1 | Alkyne Hydration. | 11 | |
9 |
2/3 | Alkyne hydroboration and halogenation. Redox reactions. Catalytic Hydrogenation. | 11, 12 | |
10 |
2/6 | Alkyne reduction. Oxidation of alkenes with peroxyacids. | 12 | |
| rev 1 | 2/7 | Rxns Review | 10-12 | p1, p2 |
|
11 |
2/8 | Hydride reducing agents. Oxidation of alkenes to diols. | 12 | |
|
2/10 | Exam 1 | Version A : Version B : Version C | |
12 |
2/13 | Ozonolysis of alkenes and alkynes. Oxidation of alcohols. | 12 | |
|
|
2/15 | No Class - Assessment Day | ||
13 |
2/17 | Radicals. Halogenation of Alkanes. | 13 | |
14 |
2/20 | Radical bromination vs chlorination. Allylic bromination with NBS. | 13 | |
15 |
2/22 | Lipid peroxidation and antioxidants. Peroxide effect on HBr addition. | 13 | |
16 |
2/24 | Dienes. Resonance theory. 1,2 vs 1,4 Addition. | 16 | |
17 |
2/27 | Stability of conjugated dienes. Diels-Alder cycloaddition. | 16 |
 |
18 |
3/1 | Electron demand in Diels-Alder rxns. The endo rule. | 16 |
|
19 |
3/3 | Benzene. Aromaticity. | 17 |
|
20 |
3/6 | MO Theory and Huckels Rule. | 17 | |
|
21 |
3/8 | More Aromatics. | 17 | |
|
3/10 | Exam 2 | answers | |
22 |
3/20 | Electrophilic aromatic substitution (EAS). | 18 | |
23 |
3/22 | Substituent effects in EAS. | 18 | |
24 |
3/24 | Disubstituted benzenes in EAS reactions. Reactions on aromatic side chains. | 18 | |
25 |
3/27 | Retake Exam 2 | ||
| lab | 3/29 | Limitations of Friedel-Crafts reactions. | 18 | |
|
26 |
3/29 | Carboxylic acids. | 19 | |
27 |
3/31 | Reduction of carbonyl compounds | 20 | |
28 |
4/3 | Organometallic Compounds - The Grignard Reagent | 20 | |
| 29 | 4/5 | Organometallic Compounds - Organocuprates | 20 | |
|
4/7 | Exam 3 | 18-20 | answers |
30 |
4/10 | Naming of Aldehydes and Ketones. Addition oh HCN and the Wittig Reaction. | 21 | |
31 |
4/12 | Addition of amines and alcohols to aldehydes and ketones. | 21 | |
|
32 |
4/17 | Carboxylic acid derivatives naming and reactions. | 22 | |
|
33 |
4/19 | Interconversion of carboxylic acid derivatives. | 22 | |
| 34 | 4/21 | Mechanism of Nitrile Hydrolysis. Enolate ions as nucleophiles: alpha halogenation. | 22, 23 | |
| 35 | 4/24 | Enolate ions as nucleophiles: alkylation and addition to aldehydes and ketones. | 24 | |
| 36 | 4/26 | Enolate ions as nucleophiles: acyl substitution (Boom Boom) | 24 | |
| 4/28 | Exam 4 | 21-24 | ||
| 5/1 | Final Exam |
